Larissa A. Tsvetkova

Immunization is one of the most significant achievements of public health over the last 100 years. Recently, however, people have been increasingly refusing to vaccinate. There are a large number of separate studies on how pervasive this behavior is and what fac- tors influence it, but no systematic review has been undertaken so far that looked at these studies as a whole. To conduct an analysis of studies that examine vaccine refusal and negative attitudes towards vaccination, focusing on the methodological approaches to the study of these problems and evaluation of their quality. A systematic review of English-language studies published between 1980 and 2015, using the Web of ScienceTM Core Collection database. The final review dealt with 31 papers. The studies in question were mainly conducted in North America and Western Europe. They were published three years after conclusion, on average. We have identified five different approaches to the study of these problems: 1) studies of parents’ attitudes and behavior; 2) analysis of vaccination records; 3) studies of attitudes and behavior among the general population; 4) studies of medical professionals’ attitudes, behavior, and experience; and 5) others. We found that theoretical models were not commonly used at the planning stage, while the studies also lacked a common approach to the operationalization of vaccine refusal, as well as of negative attitudes towards vaccination. Several promising directions have been identified for future studies on vaccine refusal and negative attitudes towards vac- cination. 

The research literature suggests that institutions for children left without parental care do not provide environments that adequately promote children’s development, and that characteristics of orphanages should be considered as an environmental factor influencing developmental difficulties in children living in institutions and later in post-institutional families. This study aimed to analyze the structural characteristics of the caregiving environment in two St. Petersburg (RF) orphanages—baby homes for children from birth to 4–5 years of age (BH A and BH B), and the maintenance of the structural interventions that were implemented in BH A during 2000-05 (The St. Petersburg–USA Orphanage Research Team, 2008). Both institutions belong to the Ministry of Health and are managed under the same medical regulations, providing about the same quality of medical care and nutrition. The results of the study show that the number of children living in each ward (4 to 6 in BH A and 5 to 8 in BH B), and the child–caregiver ratio (2 to 3 for BH A and 2.5 to 4 for BH B) in the two baby homes are about the same, while BH A have fewer staff members who are assigned to the ward (6–8 vs. 9–14 in BH B). The ward assistant teachers in BH A are assigned as the primary caregivers, working 5 days a week (39 hrs) vs. about 25 hrs a week for assistant teachers in BH B. While living in the baby home, children in BH A are integrated by age and disability (vs. segregation by age and partial disability integration in BH B), and are assigned to one ward (meaning the same caregivers, peers, rooms, etc.), while in BH B the children change their ward when they reach a certain age or developmental milestone (number of wards children experienced M(SD) = 1.1 (0.2) in BH A and 2.7 (1.1) in BH B). Our results support the hypothesis that the structural characteristics of institutional environment in the two baby homes are different, and that in comparison with BH B, the structural characteristics of BH A show more caregiving stability and consistency. The results also show that the interventions implemented in BH A within the St. Petersburg–USA Orphanage Research Project were maintained for many years after the project was finished. The specific features of an institutional caregiving environment should be taken into consideration in studies of the mental health and bio-behavioral development of children in institutions and postinstitutional families.

Today in Russia and all over the world significant efforts are invested in building biobanks—specialized facilities for storing biological materials for research and medical purposes. The successful functioning of biobanks depends directly on people’s willingness to donate their biological materials. No previous studies of people’s attitudes toward donations to biobanks have been undertaken in Russia. The goal of this study was to measure attitudes toward biobank donation among young Russians and to evaluate potential sociodemographic and personality factors that play a role in a person’s readiness to become a donor. Data from 542 students at Saint Petersburg State University were collected from group-administered paper-and-pencil questionnaires. Only one-fifth of the students knew about the existence of biobanks, while roughly the same number believed they might have heard something about them but were not absolutely certain. However, the students indicated a relatively high level of readiness to become biobank donors (74%). Willingness to be a biobank donor was correlated significantly with studying biology and was just modestly correlated with students’ values. In addition, we found gender-specific differences in the biobank characteristics that students felt were important in making a decision about whether to donate. The study demonstrated that today the attitudes of the general population (at least, those of the subgroup studied, students) do not pose a problem for the further development of biobanking in Russia.